Talk:Rune
I have used this fix recently for Rune Classic and Rune Gold, and while it fixes the positional audio, it also breaks some sound effects/music in some scenes, and character dialogue goes off synch, sadly.
There is a way to remove the CD-checking in the retail releases of Rune and Halls of Valhalla by editing the game's *ini file, but I'm not sure if it's alright to mention it on the game's wiki page if it's deemed illegal.
Yes, that sort of method have been covered for various other games (e.g. Deus Ex).